Helmholtz Zentrum München

New Study: Father's Diet Before Conception Influences Children's Health

Press Release: Restless Legs Syndrome: Genetic Discoveries Advance Treatment and Risk Prediction

Researchers at Helmholtz Munich and the Technical University of Munich (TUM) together with international collaborators have conducted the largest genetic investigation of the restless legs syndrome to date. Their findings, ...

New Study: Night-time heat significantly increases the risk of stroke

Advanced Brain Science Without Coding Expertise

Asthma in Children: Researchers Envision Novel Drug to Reduce the Risk of the Disease

Asthma in Children: Researchers Envision Novel Drug to Reduce the Risk of the Disease Scientists have reached a milestone in the research of childhood asthma. For the first time, they have clarified how a certain genetic defect in children initially leads to frequent infections and later to asthma. The study, published in the American Journal of Respiratory and ...

Scientists Reveal Adipocyte's Metabolic Role and Identify Treatment Targets

Rising Focus on 'Inceptor' as a Type 2 Diabetes Therapeutic Target

Therapeutic Vaccine for Chronic Hepatitis B Enters Clinical Trial

What Our Genetic Information Tells Us About Type 2 Diabetes Risk and Complications

Cells of the Future: A Key To Reprogramming Cell Identities

New Source of Stem Cells in Injury-Affected Brains of Patients

Understanding the Role of GIP in Managing Diabetes and Obesity

The increasing amount of patients with obesity and type 2 diabetes benefit greatly from the recently developed GIPR:GLP-1R co-agonists. These novel compounds lead to substantial weight loss, offering a revolutionary approach to patients worldwide. Although the hormone glucose-dependent insulinotropic polypeptide (GIP) was already shown by Helmholtz Munich scientists to decrease body weight via the brain GIP receptor, the ...

Interpreting Large-Scale Medical Datasets: ScPoli Enables Multi-Scale Representations of Cells and Samples

The increasing amount of data recorded in medical research can only lead to scientific breakthroughs and essential therapies for patients if interpreted and analyzed correctly. Computer scientists at Helmholtz Munich developed a generative model named scPoli (single-cell population level integration), that performs ...

DeepMB: A Deep Learning Framework For High-Quality Optoacoustic Imaging in Real-Time

Press Release: Exercise and Muscle Regulation: Implications for Diabetes and Obesity

How do our muscles respond at the molecular level to exercise? Researchers at Helmholtz Munich and the German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE) have unraveled the cellular basis and signaling pathways responsible for the p ositive impact of physical activity ...

Take a Deep Breath: Early Detection of Vascular Disease in Chronic Lung Disease of Premature Infants

Premature infants often struggle with breathing and require ventilatory support and oxygen therapy. Unfortunately, this might lead to lung damage resulting in lifelong consequences and chronic disease. Dr. Anne Hilgendorff’s team from Helmholtz Munich and the LMU University Hospital developed a non-invasive ...

A New Ally in Fighting Brain Diseases: Our Very Own Skull

Life Science Factory to Open a New Location in Munich in 2024

WildDISCO: Visualizing Whole Bodies in Unprecedented Detail

Climate change and heat: What is the impact on people with diabetes?

The increase in heat periods as a result of climate change can be more critical for people with diabetes than for metabolically healthy people. This is especially true at older ages. The article "Heat and diabetes" from diabinfo.de deals with helpful tips for people with diabetes ...

Potentiating Cancer Vulnerability to Ferroptosis: Off-Targeting Effects of DHODH Inhibitors

New Approach in Cancer Therapy With Innovative Mechanism-of-Action for Ferroptosis Induction

First Integrated Single-Cell Atlas of the Human Lung

Can a human organ be mapped on a single-cell level to learn about the functionality of each individual cell? And can we learn how different these cells are from person to person? Helmholtz Munich researchers and their collaborators have taken up this challenge and developed the Human Lung Cell Atlas using artificial intelligence (AI)-based techniques. This atlas elucidates the diversity of single lung cell types and ...

Unraveling the Mode of Action of Tirzepatide

Tirzepatide is a recently approved treatment for type-2 diabetes. Treatment with tirzepatide decreases body weight while improving glucose metabolism in patients with obesity and type-2 diabetes. Although the drug is designed to activate receptors for glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), the contribution of activating the GIP receptor in the overall efficacy of ...